uWSGI is a software application that “aims at developing a full stack for building hosting services”. It is named after the Web Server Gateway Interface (WSGI), which was the first plugin supported by the project.
uWSGI is often used for serving Python web applications in conjunction with web servers such as Cherokee and Nginx, which offer direct support for uWSGI’s native uwsgi protocol. For example, data may flow like this: HTTP client ↔ Nginx ↔ uWSGI ↔ Python app.
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WSGI applications
The Web Server Gateway Interface (WSGI, pronounced whiskey or WIZ-ghee) is a simple calling convention for web servers to forward requests to web applications or frameworks written in the Python programming language. The current version of WSGI, version 1.0. 1, is specified in Python Enhancement Proposal (PEP) 3333.